Causes of hypertension in older adults, 1905_HYPERTENSION
University of Illinois at Chicago Rövid összefoglaló This research is,being done to better understand how antioxidants vitamins C, E and Alpha Lipoic Acid af,f,ect the heart,and arteries.
For this study, we will obtain blood samples to measure oxidative stress markers substances in the blood that are linked to oxidative stresscholesterol, insulin and blood glucose sugaras well as measure how well the causes of hypertension in older adults and arteries are working following supplementation with the antioxidants. Our central hypothesis is that acute antioxidant supplementation will improve arterial function at rest and during exercise in African Americans without an impact of age, whereas aging will modify these effects in Caucasians.
Kaiser Permanente Summary: Expanding blood pressure screenings to non-primary care settings can help identify more patients with high blood pressure, commonly called hypertension, and could contribute to better hypertension control and management, according to a study. Share: FULL STORY Expanding blood pressure screenings to non-primary care settings causes of hypertension in older adults help identify more patients with high blood pressure, commonly called hypertension, and could contribute to better hypertension control and management, according to a Kaiser Permanente study published today in The Journal of Clinical Hypertension. The study reported the prevalence of hypertension and compared the characteristics of those patients identified with hypertension in a non-primary care setting to those identified in primary care settings. Of the patients studied,were found to have high blood pressure by the end of the two-year study period. Of these, 83 percent were diagnosed in a primary care setting and 17 percent in a non-primary care setting.
Részletes leírás The overall goal of this application is to investigate the effect of aging on how acute antioxidant supplementation affects decrements in arterial function observed in African Americans AA. Additionally, this application will facilitate the applicant's emergence as an independent investigator in integrative clinical physiology. Oxidative stress OScontributes to hypertension, diabetes, heart failure, atherosclerosis, sepsis and aging.
- Его личность, видимо, была могучей и безмерно привлекательной, если он смог вдохновить в равной мере как людей, так и негуманоидов.
- Он не причинит тебе никакого вреда; но может не прийтись по вкусу.
- Klinikai vizsgálat a Healthy: Antioxidant, Placebo - Klinikai vizsgálatok nyilvántartása - ICH GCP
- В эту ночь Хилвар с Олвином уже не заснули и с первыми же лучами солнца свернули лагерь.
- Даже Хилвар, казалось, немного растерялся среди огромных деревьев, которые заслоняли свет, отбрасывая на землю озерца тени.
Increased OS leads to the development of endothelial dysfunction and subsequent development of cardiovascular disease through the inactivation of nitric oxide NO by superoxide O2 and other free radicals.
African Americans AA have increased OS and inflammation in vivo and in vitro, and have a lower serum concentration of most antioxidants.
Endothelium-derived NO is a vasodilator and inhibits monocyte adhesion and platelet activity and therefore is important in the maintenance of vascular homeostasis. These specific differences in OS could be a contributing causes of hypertension in older adults to the high prevalence of cardiovascular disease, especially hypertension and heart failure, observed in AA.
Aging causes increases in OS, endothelial dysfunction, and decreased arterial compliance, thus increasing the risk of cardiovascular disease. Acute supra-physiological dosages of antioxidants have been shown to transiently restore endothelial function in older adults and patients with coronary artery disease and tejszérum és magas vérnyomás by scavenging free radicals.
However, it is unknown if acute antioxidant supplementation can diminish differences in vascular function between AA and Caucasians CA. It is also unknown if acute antioxidant supplementation with known efficacy will differentially affect blood flow in AA vs CA during exercise. Átfogó állapot.